基础兽医学系

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  • 唐博教授
  • 性别:女
  • 职称:教授
  • 硕导/博导:博导
  • 学科专业:基础兽医学
  • 最高学位:博士
  • 研究方向:动物早期胚胎发育与表观遗传学
  • 最高学历:研究生
  • 邮箱:tang_bo@jlu.edu.cn

讲授课程

本科生:动物学、发育生物学

硕士生:干细胞生物学

教育经历

1996.9-2000.7,内蒙古农业老员工命科学学院,学士学位;

2001.9-2004.7,内蒙古农业大学动物医学与科学学院,基础兽医学专业硕士学位;

2004.9-2007.9,内蒙古农业大学动物医学与科学学院,基础兽医学专业博士学位;

工作经历

2007.7-2011.9,威廉希尔williamhill畜牧兽医学院,讲师;

2011.10-2018.9,william威廉亚洲,副教授;

2018.10-现今,william威廉亚洲,教授;

科研项目

1.5-羟色胺(5-HT)对猪植入前胚胎表观遗传的影响和机制研究,2021年度吉林省教育厅科学研究项目(课题编号:JJKH20211136KJ),经费额度:2.5万(2021.1.1-2022.12.31)(进行)

2.Tet3调节的DNA去甲基化对牛体细胞核移植胚胎早期发育的影响和机制研究,国家自然基金面上项目(课题编号:31472093),经费额度:82万(2015.01-2018.12)(结题)

3.猪克隆胚胎WT1基因组蛋白乙酰化的研究,第三批博士后特别资助项目(课题编号:201003536),经费额度:10万(2011-2013)(结题)

4.梅花鹿克隆胚胎Kcnq1ot1印记基因DNA甲基化研究,第四十五博士后基金面上项目二等资助(课题编号:20090451135),经费额度:3万(2010.01-2012.12)(结题)

5.金黄地鼠克隆胚胎Kcnq1ot1印记基因DNA甲基化研究,2009年博士点新教师基金(课题编号:20090061120010),经费额度:3.6万(2010.01-2012.12)(结题)

6.地鼠克隆胚胎Kcnq1ot1印记基因的DNA甲基化研究,国家自然基金(青年基金)(课题编号:30901056),经费额度:20万(2010.01-2012.12)(结题)

7.牛体细胞核移植技术的研究,威廉希尔williamhill农学部引进人才基金(编号:4305050102B8),经费额度:5万元(2007.10-2012.12)(结题)

学术论文

1.Yu Han, Meng Zhang, Jiahui Duan, Leyi Li, Jinge Du, Hui Cheng, Sheng Zhang, Yanhui Zhai, Xinglan An, Qi Li, Xueming Zhang, Ziyi Li andBo Tang1*.Maternal Prepregnancy 5-Hydroxytryptamine Exposure Affects the Early Development of the Fetus.Frontiers in physiology.2022(二区)

2.Hui Cheng,Yu Han,Jian Zhang,Sheng Zhang,Yanhui Zhai,Xinglan An,Qi Li,Jiahui Duan,Xueming Zhang,Ziyi Li,Bo Tang*,Haiqing Shen.Effects of dimethyl sulfoxide (DMSO) on DNA methylation and histone modification in parthenogenetically activated porcine embryos.Reprod Fertil Dev . 2022 Apr 11.

3.Jian Zhang,Linlin Hao,Qian Wei,Sheng Zhang,Hui Cheng,Yanhui Zhai,Yu Jiang,Xinglan An,Ziyi Li,Xueming Zhang*,Bo Tang*.TET3 overexpression facilitates DNA reprogramming and early development of bovine SCNT embryos,Reproduction,2020, Sep;160(3):379-391.(二区,IF:3.2)

4.Cheng H,Zhang J,Zhang S,An X,Jiang Y, Zhai Y, Zhang Z, Ma X , Zhang X, Li Z ,Tang B*.Tet3 is required for normal in vitro fertilization preimplantation embryos development of bovine. Molecular Reproduction and Development.2019 Jan 20.2019 Mar;86(3):298-307(三区,IF:2.12)

5.Cheng H,Wang Y,Zhang J,Zhang S,Ma X,An X,Man X,Zhang X,Li Z,Tang B*.Effects of PRDM14 Silencing on Parthenogenetically Activated Porcine Embryos.Cell Reprogram.2018 Oct 16. doi: 10.1089/cell.2018.0029. [Epub ahead of print](四区,IF:1.43)

6.Lu-Yuan Peng, Meng Yuan, Zhen-Qiang Cui, Zong-Mei Wu, Zhen-Jiang Yu, Ke Song,Bo Tang∗, Ben-Dong Fu. Rutin inhibits quorum sensing, biofilm formation and virulence genes in avian pathogenic Escherichia coli.Microb Pathog. 2018, 119: 54-59. (Epub 2018 Apr 06): https://doi.org/10.1016/j.micpath.2018.04.007(四区,IF:2.332)

7.Zhang J,Zhang S,Wang Y,Cheng H,Hao L,Zhai Y,Zhang Z,An X,Ma X,Zhang X,Li Z,Tang B*. Effect of TET inhibitor on bovine parthenogenetic embryo development. PLoS One. 2017 Dec 21;12(12):e0189542. doi: 10.1371/journal.pone.0189542. eCollection 2017.(二区,IF:2.806)

8. An X, Ma K, Zhang Z, Zhao T, Zhang X,Tang B*, Li Z*. miR-17, miR-21, and miR-143 Enhance Adipogenic Differentiation from Porcine Bone Marrow-Derived Mesenchymal Stem Cells. DNA Cell Biol. 2016 Aug;35(8):410-6. PubMed PMID: 27093346.(三区,IF:2.574)

9.Cai H,Tang B, Wu JY, Zhao XX, Wang ZZ, An XL, Lai LX, Li ZY, Zhang XM. Enrichment and in vitro features of the putative gonocytes from cryopreserved testicular tissue of neonatal bulls. Andrology. 2016 Nov;4(6):1150-1158.(三区,IF:2.734)

10. Zhang S,Tang B, Fan C, Shi L, Zhang X, Sun L, Li Z. Effect of DNMT inhibitor on bovine parthenogenetic embryo development. Biochem Biophys Res Commun. 2015 Oct 23;466(3):505-11. PubMed PMID: 26381173.(三区,IF:2.371)

11. Pan X, Kong D, Liu L, Gao F, Zhang X,Tang B* and Li Z*. Development block of golden hamster ICSI embryos is associated with decreased expression of HDAC1, HSPA1A and MYC. Cell Biol Int.(Cell Biology International)2014 Nov;38(11):1280-90. PubMed PMID: 24890342.(四区,IF:1.663)

12. Ying Liu, Limei Liu, Xin Ma, Yupeng Yin,Bo Tang*,Ziyi Li*. Characteristics and neural-like differentiation of mesenchymal stem cells derived from foetal porcine bone marrow.Biosci Rep, 2013 Mar, 33 (2).(三区,IF:2.446)

13. Xin Ma, Peng Zhang, Guangqi Song, Yue Chen, Zhongwei Wang, Yupeng Yin, Delong Kong, Sheng Zhang, Zhihui Zhao, Hongsheng Ouyang,Bo Tang*,Ziyi Li*. The Construction and Expression of Lysine-Rich Gene in the Mammary Gland of Transgenic Mice.DNA Cell Biol. 2012 Aug; 31(8):1372-83(三区,IF: 2.344)

14. Limei Liu, Guangqi Song, Fei Gao, Jiyu Guan,Bo Tang*,Ziyi Li*. Transient exposure to sodium butyrate after germinal vesicle breakdown improves meiosis but not developmental competence in pig oocytes.Cell Biol. Int., 2012 Jul, 36(5), 483-490(四区,IF: 1.64)

15. Limei Liu, Ying Liu, Fei Gao, Guangqi Song, Jiang Wen, Jiyu Guan, Yupeng Yin, Xin Ma,Bo Tang*,Ziyi Li*. Embryonic Development and Gene Expression of Porcine SCNT Embryos Treated With Sodium Butyrate.J Exp Zool B Mol Dev Evol.2012 May, 318(3):224-234(二区,IF: 2.123)

16.Peng Zhang, Li Su, Zhongwei Wang, Sheng Zhang, Jiyu Guan, Yue Chen, Yupeng Yin, Fei Gao,Bo Tang*,Ziyi Li*. The Involvement of 5-Hydroxymethylcytosine in Active DNA Demethylation in Mice.Biol Reprod, 2012 Apr ,86(4):104,1-9(二区,IF: 4.027)

17.Yupeng Yin, Lina Tang, Jiabao Zhang,Bo Tang*, Ziyi Li*.Molecular Cloning and Gene Expression Analysis of Ercc6l in Sika Deer (Cervus nippon hortulorum).PLoS ONE, 2011, 6(6): e20929(二区,IF: 4.092)

18. Zhongwei Wang, Tianchuang Zhao, Peng Zhang, Sheng Zhang, Jiyu Guan, Xin Ma, Yupeng Yin, Jiabao Zhang,Bo Tang* andZiyi Li*. Histone Deacetylase 1 Down-Regulation on Developmental Capability and Histone Acetylation in Bovine Oocytes and Parthenogenetic Embryos.Reprod Dom Anim,2011, 46: 1022-1028(三区,IF: 1.356)

19. Jiang Wen, Juan Liu, Guangqi Song, Limei Liu,Bo Tang* andZiyi Li*. Effects of 6-bromoindirubin-30-oxime on the maintenance of pluripotency of porcine embryonic germ cells in combination with stem cell factor, leukemia inhibitory factor and fibroblast growth factor.Reproduction, 2010, 139:1039-1046(二区,IF: 3.049)

著作教材

1.参编《动物疾病病理诊断学》(高丰,贺文琦 主编,北京,科学出版社,2010.01)出版号:9787030266538;

2.参编《猫病学》(安铁洙,谭建华,张乃生 主编,北京,中国农业出版社2010.11)出版号:9787109151178;

3.副主编 校内教材《动物形态学实验指导》(成军等 主编,长春,威廉希尔williamhill出版社,2010.01);

获奖情况

1.吉林省科学技术进步二等奖,项目:转基因克隆动物及体细胞克隆胚胎重编程的分子机制研究。参与人排名3/8。证书编号:2015Z20013;

2.吉林省自然科学学术成果二等奖,项目:哺乳动物体细胞核移植胚胎重编程机制的研究,参与人排名:2/7。证书编号:20142095;

3.吉林省自然科学学术成果奖三等奖,项目:5-羟甲基胞嘧啶参与小鼠DNA去甲基化,参与人排名:9/10。证书编号:20133095;

4.2021年威廉希尔williamhill第二届智慧课堂教学创新大赛暨“长春市职工技能大赛”三等奖。

社会兼职

国家自然科学基金网上评审专家;

中国动物学会吉林省动物学分会理事;

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