1997-2001，内蒙古农业大学，动物医学，本科

2001-2004，中国人民解放军军需大学，预防兽医学，硕士

2006-2009，威廉希尔williamhill，基础兽医学，博士

2020-至今，威廉希尔williamhill，“唐敖庆学者”卓越教授B岗

2017-至今，william威廉亚洲，副经理

2017-至今，国家级动物科技实验教学示范中心，主任

2013-至今，威廉希尔williamhill，教授

2011-2012，美国佐治亚大学，博士后

2004-2013，威廉希尔williamhill，助教、讲师、副教授

1. 国家自然基金面上项目，神经细胞内质网应激在PHEV感染过程中的作用及其机制（32172828） 2022.1-2025.12，

2. 国家自然基金面上项目，PHEV入侵神经细胞胞吞途径及其胞内运输的分子机制（31772704） 2018.1-2021.12

3. 国家自然基金面上项目，胶质细胞在猪血凝性脑脊髓炎病毒感染CNS中的免疫应答机制（31472194） 2015.1-2018.12

4. 国家自然基金面上项目，猪血凝性脑脊髓炎病毒感染过程中的免疫应答机制研究（31172291） 2012.1-2015.12

5. 国家自然基金青年基金，川金丝猴源柯萨奇B3病毒感染猕猴的病理及血液指标变化特征（30901060） 2010.1-2012.12

6. 国家重点研发计划项目子课题，仔猪腹泻冠状病毒感染及其致病机理（2016YFD0500102） 2016.1-2020.12

7. 吉林省重点研发项目，猪血凝性脑脊髓炎病毒DNA疫苗的研制及其免疫保护力评价（20210202041NC），2021.7-2024.6

8. 吉林省自然科学基金项目，内吞介导猪血凝性脑脊髓炎病毒侵入神经细胞的分子机制（20180101270JC） 2018.1-2020.12

9. 吉林省自然科学基金项目，猪血凝性脑脊髓炎病毒感染小鼠脑组织microRNA组学研究（20130101106JC） 2013.1-2015.12

2016年以来发表的代表性文章：

1. The PERK/PKR-eIF2α pathway negatively regulates porcine hemagglutinating encephalomyelitis virus replication by attenuating global protein translation and facilitating stress granule formation. Journal of Virology. 2022-01-12, J Virol 96:1: e01695-21.

2. Evidence of microglial immune response following coronavirus PHEV infection of CNS. Frontiers in Immunology, 2022-01-10, 12, 804625. DOI: 10.3389/fimmu.2021.804625.

3. Cell-surface glycans act as attachment factors for porcine hemagglutinating encephalomyelitis virus. Veterinary Microbiology. 2022 Feb, 265: 109315.

4. Microtubule depolymerization limits porcine betacoronavirus PHEV replication. Veterinary Microbiology. 2022 April 27, 269: 109448.

5. Porcine Haemagglutinating Encephalomyelitis Virus Triggers Neural Autophagy Independent of ULK1. Journal of Virology. 2021 Sep 9; 95(19): e00851-21. pp.JVI0085121.

6. Orf virus ORF120 protein positively regulates the NF-κB pathway by interacting with G3BP1. Journal of Virology. 2021 Sep 9; 95(19): e00153-21.

7. Prevalence and Characterization of Cryptosporidium Species in Tibetan Antelope (Pantholops hodgsonii). Frontiers in Cellular and Infection Microbiology, 2021, 11:713873. doi: 10.3389/fcimb.2021.713873.

8. Host factor cyclophilin B affects Orf virus replication by interacting with viral ORF058 protein. Veterinary Microbiology, July 2021, 258: 109099.

9. Porcine hemagglutinating encephalomyelitis virus induces atypical autophagy via opposite regulation of expression and nuclear translocation of transcription factor EB. Veterinary Microbiology, 2021 Apr; 255:109015.

10. DDIT3 targets innate immunity via the DDIT3-OTUD1-MAVS pathway to promote bovine viral diarrhea virus replication. Journal of Virology. 2021. J Virol 95: e02351-20.

11. Porcine Haemagglutinating Encephalomyelitis Virus Deactivates Transcription Factor IRF3 and Limits Type I Interferon Production. Veterinary Microbiology, 2021 Jan; 252: 108918.

12. miR-142a-3p promotes the proliferation of porcine hemagglutinating encephalomyelitis virus by targeting Rab3a. Archives of Virology, 2020 Feb; 165(2):345-354.

13. MiR-10a-5p-Mediated Syndecan 1 Suppression Restricts Porcine Hemagglutinating Encephalomyelitis Virus Replication. Frontiers in Microbiology. 2020, 11: 105.

14. An experimental model of neurodegenerative disease based on porcine hemagglutinating encephalomyelitis virus-related lysosomal abnormalities. Molecular Neurobiology. 2020 Sep 2, 57(12): 5299-5306.

15. Porcine hemagglutinating encephalomyelitis virus activation of the integrin α5β1-FAK-Cofilin pathway causes cytoskeletal rearrangement to promote its invasion of N2a cells. Journal of Virology. 2019 Feb 19; 93(5). pii: e01736-18.

16. ATN-161 reduces virus proliferation in PHEV-infected mice by inhibiting the integrin α5β1-FAK signaling pathway. Veterinary Microbiology, 2019 Jun; 233: 147-153.

17. Cellular microRNA bta-miR-2361 inhibits bovine herpesvirus 1 replication by directly targeting EGR1 gene. Veterinary Microbiology, 2019 Jun; 233: 174-183.

18. Genomic characterization of two Orf virus isolates from Jilin province in China. Virus Genes, 2019 Aug; 55(4):490-501.

19. Ulk1 Governs Nerve Growth Factor/TrkA Signaling by Mediating Rab5 GTPase Activation in Porcine Hemagglutinating Encephalomyelitis Virus-Induced Neurodegenerative Disorders. Journal of Virology. 2018 Jul 31; 92(16). pii: e00325-18.

20. Genomic characterization and pathogenicity of a porcine hemagglutinating encephalomyelitis virus strain isolated in China. Virus Genes. 2018 Oct;54(5):672-683.

21. Porcine hemagglutinating encephalomyelitis virus enters Neuro-2a cells via clathrin-mediated endocytosis in a Rab5-, cholesterol-, and pH-dependent manner. Journal of Virology. 2017 Nov 14; 91(23). pii: e01083-17.

22. Induction of atypical autophagy by porcine hemagglutinating encephalomyelitis virus contributes to viral replication. Frontiers in Cellular and Infection Microbiology. 2017, 7:56.

23. miR-21a-5p contributes to porcine hemagglutinating encephalomyelitis virus proliferation via targeting CASK-interactive protein1 in vivo and vitro. Frontiers in Microbiology. 2017, 8: 304.

24. miR-142-5p Disrupts Neuronal Morphogenesis Underlying Porcine Hemagglutinating Encephalomyelitis Virus Infection by Targeting Ulk1. Frontiers in Cellular and Infection Microbiology. 2017 May 3; 7:155.

25. Cyclophilin B facilitates the replication of Orf virus. Virology Journal. 2017, Jun 15; 14(1): 114.

26. Baicalin Protects Mice from Lethal Infection by Enterohemorrhagic Escherichia coli. Frontiers in Microbiology. 2017, 8:395.

27. The matrix protein of vesicular stomatitis virus inhibits host-directed transcription of target genes via interaction with the TFIIH subunit p8. Veterinary Microbiology, 2017 Sep; 208: 82-88.

28. EIF3i Affects Vesicular Stomatitis Virus Growth by Interacting with Matrix Protein. Veterinary Microbiology, 2017 Dec; 212: 59-66.

29. Development of a lateral flow immunochromatographic assay for the rapid diagnosis of Orf virus infections. Journal of Virological Methods. 2016, Jul 2; 236:10-17.

30. The evidence of porcine hemagglutinating encephalomyelitis virus induced nonsuppurative encephalitis as the cause of death in piglets. 2016, PeerJ. 2016 Sep 15; 4:e2443.

31. Role of autophagy in cellular response to infection with Orf virus Jilin isolate. Veterinary Microbiology, 2016 Sep 25; 193: 22-27.

1. 主编，《动物病理解剖学》(第二版)，科学出版社 2013.11

2. 主编，《动物疾病病理诊断学》，科学出版社 2010.01

3. 主编，《动物病理解剖学》，科学出版社 2008.08

4. 副主编，《动物病理学》(双语)，浙江大学出版社，2020.11.

5. 副主译，《马血液与细胞诊断学》(第2版)(译著)，中国农业出版社，2019.06.

6. 副主编，《动物形态学实验指导》，威廉希尔williamhill出版社 2010.01

7. 参编，《动物冠状病毒病》，中国农业出版社，2021.05.

8. 参编，《家畜病理学》(第5版)，中国农业出版社，2016.05.

9. 参编，《兽医病理学》(第5版)(译著)，中国农业出版社，2015.12；

10. 参编，《猪病学》(第十版)(译著)，中国农业大学出版社2014.08

11. 参编，《动物病理解剖学》，化学工业出版社 2011.08

12. 参编，《野生动物疫病学》，高等教育出版社 2011.05

13. 参编，《畜牧兽医专业英语听力教程》，复旦大学出版社 2009.08

14. 参编，《犬病/兽医全攻略》，中国农业出版社2009.08

1. 吉林省首批科研“春苗”人才称号；

2. 吉林省自然科学奖二等奖1项；

3. 吉林省自然科学学术成果奖一等奖1项、二等奖2项；

4. 吉林省教学成果一等奖、吉林省高等学校优秀教材奖、吉林省精品课程、威廉希尔williamhill教学成果特等奖等教学成果奖7项；

5. 吉林省省级虚拟仿真实验教学一流课程；

6. 吉林省硕士专业学位示范论文指导教师；

7. 全国老员工动物医学专业技能大赛特等奖3次，指导教师。

1. 中国病理生理学会，理事；

2. 中国病理生理学会动物病理生理学专业委员会，副主任委员；

3. 中国畜牧兽医学会兽医病理学分会，常务理事；

4. 中国畜牧兽医学会动物传染病学分会，理事；

5. 中国畜牧兽医学会生物技术学分会，理事；

6. 吉林省畜牧兽医学会，常务理事；

7. 吉林省神经科学学会，理事；

8. 吉林省高等学校教指委委员；

9. 吉林省畜牧业标准化技术委员会委员；

10. 吉林省动物疫病防控专家；

11. 《中国兽医学报》期刊编委；

12. 《Frontiers in Cellular and Infection Microbiology》期刊Review Editor。